› 6c7n

X-ray diffraction
2Å resolution

Monoclinic form of malic enzyme from sorghum at 2 angstroms resolution

Released:
DOI: 10.2210/pdb6c7n/pdb
Model geometry
Fit model/data
PDB entry 6c7n coloured by chain, front view.
PDB entry 6c7n coloured by chain, side view.
PDB entry 6c7n coloured by chain, top view.
Source organism: Sorghum bicolor
Primary publication:
Molecular adaptations of NADP-malic enzyme for its function in C4 photosynthesis in grasses.
Alvarez CE, Bovdilova A, Höppner A, Wolff CC, Saigo M, Trajtenberg F, Zhang T, Buschiazzo A, Nagel-Steger L, Drincovich MF, Lercher MJ, Maurino VG
Nat Plants 5 755-765 (2019)
PMID: 31235877

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183057 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Malic enzyme Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 613 amino acids
Theoretical weight: 67.28 KDa
Source organism: Sorghum bicolor
Expression system: Escherichia coli
UniProt:
  • Canonical: Q84LQ5 (Residues: 62-636; Coverage: 90%)
Gene name: SORBI_3003G036200
Sequence domains:

Ligands and Environments

4 bound ligands:
Ligand NAP 4 x NAP
Ligand GOL 17 x GOL
Ligand PYR 3 x PYR
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2
Unit cell:
a: 208.1Å b: 64.26Å c: 202.72Å
α: 90° β: 93.65° γ: 90°
R-values:
R R work R free
0.18 0.18 0.21
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Role of C4 photosynthetic enzyme isoforms in C3 plants and their potential applications in improving agronomic traits in crops.
Singh et al. (2022)
8 other articles

1 mention without citation

Structural and Molecular Dynamics of Mycobacterium tuberculosis Malic Enzyme, a Potential Anti-TB Drug Target.
Burley et al. (2021)