Function and Biology Details
Reaction catalysed:
Acetyl-CoA + an N-terminal-L-alanyl-[protein] = an N-terminal-N(alpha)-acetyl-L-alanyl-[protein] + CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Tetratricopeptide repeat
- GNAT domain
- N-terminal acetyltransferase A, auxiliary subunit
- Nascent polypeptide-associated complex subunit alpha-like, UBA domain
- Huntingtin-interacting protein K, UBA-like domain
- N-acetyltransferase Ard1-like
- Acyl-CoA N-acyltransferase
- Tetratricopeptide-like helical domain superfamily
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-154347 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
N-alpha-acetyltransferase 15, NatA auxiliary subunit
Molecule details ›
N-alpha-acetyltransferase 10
Molecule details ›
Chain: B
Length: 236 amino acids
Theoretical weight: 26.52 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Acetyltransferase (GNAT) family
Structure domains: Aminopeptidase
Length: 236 amino acids
Theoretical weight: 26.52 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P41227 (Residues: 1-235; Coverage: 100%)
Sequence domains: Acetyltransferase (GNAT) family
Structure domains: Aminopeptidase
Huntingtin-interacting protein K
Molecule details ›
Chain: D
Length: 129 amino acids
Theoretical weight: 14.69 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: HYPK UBA domain
Length: 129 amino acids
Theoretical weight: 14.69 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q9NX55 (Residues: 1-121; Coverage: 100%)
Sequence domains: HYPK UBA domain
