› 6caa

Electron Microscopy
3.9Å resolution

CryoEM structure of human SLC4A4 sodium-coupled acid-base transporter NBCe1

Released:
DOI: 10.2210/pdb6caa/pdb
PDB entry 6caa coloured by chain, front view.
PDB entry 6caa coloured by chain, side view.
PDB entry 6caa coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1.
Huynh KW, Jiang J, Abuladze N, Tsirulnikov K, Kao L, Shao X, Newman D, Azimov R, Pushkin A, Zhou ZH, Kurtz I
Nat Commun 9 900 (2018)
PMID: 29500354
Related structures: EMD-7441

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195385 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Electrogenic sodium bicarbonate cotransporter 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 1035 amino acids
Theoretical weight: 116.17 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9Y6R1 (Residues: 77-1079; Coverage: 93%)
Gene names: NBC, NBC1, NBCE1, SLC4A4
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-7441
Expression system: Homo sapiens

Quick links

Citations

13 review citations

A guide to plasma membrane solute carrier proteins.
Pizzagalli et al. (2021)
12 more

12 mentions without citation

Plant transporters involved in combating boron toxicity: beyond 3D structures.
Hrmova et al. (2020)
11 more