› 6ce1

X-ray diffraction
2.8Å resolution

Crystal structure of Peptidyl Arginine Deiminase Type III (PADI3)

Released:
DOI: 10.2210/pdb6ce1/pdb
PDB entry 6ce1 coloured by chain, front view.
PDB entry 6ce1 coloured by chain, side view.
PDB entry 6ce1 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural characterization of human peptidyl-arginine deiminase type III by X-ray crystallography
Rechiche O, Lee TV, Lott JS
Acta Crystallogr F Struct Biol Commun 77 334-340 (2021)

Function and Biology Details

Reaction catalysed: 
Protein L-arginine + H(2)O = protein L-citrulline + NH(3)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193943 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein-arginine deiminase type-3 Chain: A
Molecule details ›
Chain: A
Length: 686 amino acids
Theoretical weight: 77.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9ULW8 (Residues: 1-664; Coverage: 100%)
Gene names: PAD3, PADI3, PDI3
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: R32
Unit cell:
a: 115.023Å b: 115.023Å c: 328.487Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.236 0.234 0.274
Expression system: Escherichia coli BL21(DE3)

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