› 6ckv

Solution NMR

Solution NMR structure of human BOK

Released:
DOI: 10.2210/pdb6ckv/pdb
PDB entry 6ckv coloured by chain, ensemble of 20 models, front view.
PDB entry 6ckv coloured by chain, ensemble of 20 models, side view.
PDB entry 6ckv coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis.
Zheng JH, Grace CR, Guibao CD, McNamara DE, Llambi F, Wang YM, Chen T, Moldoveanu T
Cell Rep 23 2083-2094.e6 (2018)
PMID: 29768206

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193977 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bcl-2-related ovarian killer protein Chain: A
Molecule details ›
Chain: A
Length: 158 amino acids
Theoretical weight: 17.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 536
UniProt:
  • Canonical: Q9UMX3 (Residues: 21-177; Coverage: 74%)
Gene names: BCL2L9, BOK
Sequence domains: Apoptosis regulator proteins, Bcl-2 family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli 536

Quick links

Citations

11 review citations

Mitochondria as multifaceted regulators of cell death.
Bock et al. (2020)
10 more

5 mentions without citation

The Mysteries around the BCL-2 Family Member BOK.
Shalaby et al. (2020)
4 more