PDB 6cst structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

Biochemical function:

DNA-directed DNA polymerase activity

Biological process:

DNA repair

Cellular component:

not assigned

Sequence domains:

Structure analysis Details

Assembly composition:

hetero hexamer (preferred)

Assembly name:

DNA polymerase kappa and DNA (preferred)

PDBe Complex ID:

PDB-CPX-119691 (preferred)

Entry contents:

1 distinct polypeptide molecule
2 distinct DNA molecules

Macromolecules (3 distinct):

DNA polymerase kappa Chains: A, B

Molecule details ›

Chains: A, B
Length: 551 amino acids
Theoretical weight: 63.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

Canonical: Q9UBT6 (Residues: 1-526; Coverage: 61%)

Gene names: DINB1, POLK
Sequence domains:

Structure domains:

DNA (5'-D(P*AP*TP*AP*CP*AP*TP*AP*CP*C)-3') Chains: C, P

Molecule details ›

Chains: C, P
Length: 9 nucleotides
Theoretical weight: 2.68 KDa
Source organism: synthetic construct
Expression system: Not provided

DNA (5'-D(P*TP*AP*CP*TP*GP*GP*TP*AP*TP*GP*TP*AP*T)-3') Chains: D, T

Molecule details ›

Chains: D, T
Length: 13 nucleotides
Theoretical weight: 4 KDa
Source organism: synthetic construct
Expression system: Not provided