Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero 300-mer (preferred)
Assembly name:
Capsid protein VP4 and Anthrax toxin receptor 1 (preferred)
PDBe Complex ID:
PDB-CPX-172341 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Anthrax toxin receptor 1
Molecule details ›
Chain: E
Length: 182 amino acids
Theoretical weight: 21.03 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain
Length: 182 amino acids
Theoretical weight: 21.03 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9H6X2 (Residues: 39-220; Coverage: 34%)
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain
Capsid protein VP1
Molecule details ›
Chain: A
Length: 258 amino acids
Theoretical weight: 28.46 KDa
Source organism: Senecavirus A
UniProt:
Length: 258 amino acids
Theoretical weight: 28.46 KDa
Source organism: Senecavirus A
UniProt:
- Canonical: Q155Z9 (Residues: 674-931; Coverage: 12%)
Capsid protein VP2
Molecule details ›
Chain: C
Length: 268 amino acids
Theoretical weight: 29.87 KDa
Source organism: Senecavirus A
UniProt:
Structure domains: Jelly Rolls
Length: 268 amino acids
Theoretical weight: 29.87 KDa
Source organism: Senecavirus A
UniProt:
- Canonical: Q155Z9 (Residues: 162-429; Coverage: 12%)
Structure domains: Jelly Rolls
Capsid protein VP3
Molecule details ›
Chain: B
Length: 238 amino acids
Theoretical weight: 26.35 KDa
Source organism: Senecavirus A
UniProt:
Structure domains: Jelly Rolls
Length: 238 amino acids
Theoretical weight: 26.35 KDa
Source organism: Senecavirus A
UniProt:
- Canonical: Q155Z9 (Residues: 435-672; Coverage: 11%)
Structure domains: Jelly Rolls
Capsid protein VP4
Molecule details ›
Chain: D
Length: 58 amino acids
Theoretical weight: 6 KDa
Source organism: Senecavirus A
UniProt:
Length: 58 amino acids
Theoretical weight: 6 KDa
Source organism: Senecavirus A
UniProt:
- Canonical: Q155Z9 (Residues: 93-150; Coverage: 3%)
