6cxl

X-ray diffraction
3.59Å resolution

anti-HIV-1 Fab 2G12 in complex with glycopeptide 10F5

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-214001 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
anti-HIV-1 Fab 2G12 light chain Chains: K, L
Molecule details ›
Chains: K, L
Length: 213 amino acids
Theoretical weight: 23.2 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
anti-HIV-1 Fab 2G12 heavy chain Chains: H, M
Molecule details ›
Chains: H, M
Length: 224 amino acids
Theoretical weight: 23.85 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: BMA, MAN
No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: I222
Unit cell:
a: 137.641Å b: 146.308Å c: 148.213Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.219 0.248
Expression system: Homo sapiens