› 6d2k

X-ray diffraction
1.55Å resolution

Crystal structure of the FERM domain of mouse FARP2

Released:
DOI: 10.2210/pdb6d2k/pdb
Model geometry
Fit model/data
PDB entry 6d2k coloured by chain, front view.
PDB entry 6d2k coloured by chain, side view.
PDB entry 6d2k coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural analyses of FERM domain-mediated membrane localization of FARP1.
Kuo YC, He X, Coleman AJ, Chen YJ, Dasari P, Liou J, Biederer T, Zhang X
OpenAccess logo Sci Rep 8 10477 (2018)
PMID: 29992992

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187567 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
FERM, ARHGEF and pleckstrin domain-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 288 amino acids
Theoretical weight: 34.2 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q91VS8 (Residues: 38-324; Coverage: 27%)
Gene names: Farp2, Kiaa0793
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 39.418Å b: 72.762Å c: 94.226Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.197 0.224
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Roles of Integrins in Gastrointestinal Cancer Metastasis.
Hou et al. (2021)
1 more

2 mentions without citation

Structural analyses of FERM domain-mediated membrane localization of FARP1.
Kuo et al. (2018)
1 more