6d58

X-ray diffraction
2.39Å resolution

Crystal structure of a Fc fragment of Human IgG3

Released:
Source organism: Homo sapiens
Entry authors: Gohain N, Tolbert WD, Pazgier M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-134883 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Immunoglobulin heavy constant gamma 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 214 amino acids
Theoretical weight: 24.25 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01860 (Residues: 164-375; Coverage: 48%)
Gene name: IGHG3
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN, FUC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL14-1
Spacegroup: P212121
Unit cell:
a: 49.59Å b: 80.678Å c: 136.029Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.234 0.286
Expression system: Homo sapiens