› 6dbd

X-ray diffraction
1.76Å resolution

Crystal Structure of VHH R326

Released:
DOI: 10.2210/pdb6dbd/pdb
Model geometry
Fit model/data
PDB entry 6dbd coloured by chain, front view.
PDB entry 6dbd coloured by chain, side view.
PDB entry 6dbd coloured by chain, top view.
Source organism: Lama glama
Primary publication:
Structural basis of VHH-mediated neutralization of the food-borne pathogen Listeria monocytogenes.
King MT, Huh I, Shenai A, Brooks TM, Brooks CL
J Biol Chem 293 13626-13635 (2018)
PMID: 29976754

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-231500 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
nanobody VHH R326 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 129 amino acids
Theoretical weight: 14.17 KDa
Source organism: Lama glama
Expression system: Escherichia coli BL21

Ligands and Environments

2 bound ligands:
Ligand NA 1 x NA
Ligand ACT 1 x ACT
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P6522
Unit cell:
a: 97.701Å b: 97.701Å c: 243.8Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.161 0.16 0.182
Expression system: Escherichia coli BL21

Quick links

Citations

8 review citations

NANOBODIES®: A Review of Diagnostic and Therapeutic Applications
Jin et al. (2023)
7 more

2 mentions without citation

Single Domain Antibody application in bacterial infection diagnosis and neutralization.
Qin et al. (2022)
1 more