› 6dg6

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-166589 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neoleukin-2/15 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 104 amino acids
Theoretical weight: 12.11 KDa
Source organism: synthetic construct
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P212121
Unit cell:
a: 73.73Å b: 86.8Å c: 92.31Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.204 0.226
Expression system: Escherichia coli

Quick links

Citations

69 review citations

Recent advances and discoveries in the mechanisms and functions of CAR T cells.
Larson et al. (2021)
68 more

5 mentions without citation

Engineering protein-based therapeutics through structural and chemical design.
Ebrahimi et al. (2023)
4 more