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Electron Microscopy
3.2Å resolution

Cryo-EM structure of the mitochondrial calcium uniporter MCU from the fungus Cyphellophora europaea

Released:
Related structures: EMD-7971

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-197731 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium uniporter protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 352 amino acids
Theoretical weight: 39.64 KDa
Source organism: Cyphellophora europaea CBS 101466
Expression system: Komagataella pastoris
UniProt:
  • Canonical: W2SDE2 (Residues: 1-346; Coverage: 100%)
Gene name: HMPREF1541_00236
Sequence domains: Mitochondrial calcium uniporter

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-7971
Expression system: Komagataella pastoris