Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131757 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Kelch domain-containing protein 2
Molecule details ›
Chains: A, B
Length: 363 amino acids
Theoretical weight: 41.35 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Galactose oxidase, central domain
Length: 363 amino acids
Theoretical weight: 41.35 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q9Y2U9 (Residues: 1-362; Coverage: 89%)
Sequence domains: Galactose oxidase, central domain
Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment
Molecule details ›
Chains: C, D
Length: 6 amino acids
Theoretical weight: 529 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 6 amino acids
Theoretical weight: 529 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: O94782 (Residues: 666-671; Coverage: 1%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 8.2.1
Spacegroup:
P21
Expression systems:
- Trichoplusia ni
- Not provided
