› 6drf

Solution NMR

Structure of human Retinal Degeneration 3(RD3) Protein

Released:
DOI: 10.2210/pdb6drf/pdb
PDB entry 6drf coloured by chain, ensemble of 10 models, front view.
PDB entry 6drf coloured by chain, ensemble of 10 models, side view.
PDB entry 6drf coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four-helix bundle.
Peshenko IV, Yu Q, Lim S, Cudia D, Dizhoor AM, Ames JB
J Biol Chem 294 2318-2328 (2019)
PMID: 30559291

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182259 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein RD3 Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 16.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7Z3Z2 (Residues: 19-153; Coverage: 69%)
Gene names: C1orf36, RD3
Sequence domains: RD3 protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 75%
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Regulation of retinal membrane guanylyl cyclase (RetGC) by negative calcium feedback and RD3 protein.
Dizhoor et al. (2021)
2 more

2 mentions without citation

Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four-helix bundle.
Peshenko et al. (2019)
1 more