› 6e80

X-ray diffraction
2.9Å resolution

Crystal structure of the Corn aptamer in unliganded state

Released:
DOI: 10.2210/pdb6e80/pdb
PDB entry 6e80 coloured by chain, front view.
PDB entry 6e80 coloured by chain, side view.
PDB entry 6e80 coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Binding between G Quadruplexes at the Homodimer Interface of the Corn RNA Aptamer Strongly Activates Thioflavin T Fluorescence.
Sjekloća L, Ferré-D'Amaré AR
Cell Chem Biol 26 1159-1168.e4 (2019)
PMID: 31178406

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197076 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (36-MER) Chain: A
Molecule details ›
Chain: A
Length: 36 nucleotides
Theoretical weight: 11.79 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

5 bound ligands:
Ligand IRI 3 x IRI
Ligand K 1 x K
Ligand MG 4 x MG
Ligand ACT 2 x ACT
Ligand IR 2 x IR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: R32
Unit cell:
a: 93.012Å b: 93.012Å c: 66.56Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.258 0.252 0.307
Expression system: Not provided

Quick links

Citations

3 review citations

The emerging structural complexity of G-quadruplex RNAs.
Banco et al. (2021)
2 more

5 mentions without citation

Structural Insights into RNA Dimerization: Motifs, Interfaces and Functions.
Bou-Nader et al. (2020)
4 more