› 6eik

X-ray diffraction
1.52Å resolution

A de novo designed heptameric coiled coil CC-Hept-I24E

Released:
DOI: 10.2210/pdb6eik/pdb
PDB entry 6eik coloured by chain, front view.
PDB entry 6eik coloured by chain, side view.
PDB entry 6eik coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
De Novo-Designed α-Helical Barrels as Receptors for Small Molecules.
Thomas F, Dawson WM, Lang EJM, Burton AJ, Bartlett GJ, Rhys GG, Mulholland AJ, Woolfson DN
ACS Synth Biol 7 1808-1816 (2018)
PMID: 29944338

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-166676 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CC-Hept-I24E Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 32 amino acids
Theoretical weight: 3.36 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand GOL 4 x GOL
Ligand FMT 1 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P42212
Unit cell:
a: 62.21Å b: 62.21Å c: 108.68Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.164 0.161 0.208
Expression system: Not provided

Quick links

Citations

5 review citations

Protein Design: From the Aspect of Water Solubility and Stability.
Qing et al. (2022)
4 more

1 mention without citation

Robustification of RosettaAntibody and Rosetta SnugDock.
Jeliazkov et al. (2021)