› 6eun

X-ray diffraction
2.45Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145139 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neisseria adhesin A Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 156 amino acids
Theoretical weight: 16.71 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DV44 (Residues: 24-170; Coverage: 39%)
Gene names: nadA, nadA3

Ligands and Environments

8 bound ligands:
Ligand CL 1 x CL
Ligand EDO 13 x EDO
Ligand PO4 4 x PO4
Ligand CIT 1 x CIT
Ligand 2PE 1 x 2PE
Ligand P4G 2 x P4G
Ligand PEG 3 x PEG
Ligand MPD 2 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 69.761Å b: 39.778Å c: 255.494Å
α: 90° β: 95.25° γ: 90°
R-values:
R R work R free
0.2 0.199 0.224
Expression system: Escherichia coli

Quick links

Citations

3 review citations

The Development of a Vaccine Against Meningococcus B Using Reverse Vaccinology.
Masignani et al. (2019)
2 more

3 mentions without citation

Vaccines against Meningococcal Diseases.
Pizza et al. (2020)
2 more