› 6f0d

X-ray diffraction
1.9Å resolution

Crystal structure of a llama VHH antibody BCD090-M2 against human ErbB3 in space group P1 with cadmium ions

Released:
DOI: 10.2210/pdb6f0d/pdb
Model geometry
Fit model/data
PDB entry 6f0d coloured by chain, front view.
PDB entry 6f0d coloured by chain, side view.
PDB entry 6f0d coloured by chain, top view.
Source organism: Lama glama
Primary publication:
Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor.
Eliseev IE, Yudenko AN, Vysochinskaya VV, Svirina AA, Evstratyeva AV, Drozhzhachih MS, Krendeleva EA, Vladimirova AK, Nemankin TA, Ekimova VM, Ulitin AB, Lomovskaya MI, Yakovlev PA, Bukatin AS, Knyazev NA, Moiseenko FV, Chakchir OB
OpenAccess logo F1000Res 7 57 (2018)
PMID: 30430004

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214045 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
VHH antibody BCD090-M2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 128 amino acids
Theoretical weight: 13.97 KDa
Source organism: Lama glama
Expression system: Escherichia coli

Ligands and Environments

1 bound ligand:
Ligand CD 2 x CD
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: BRUKER IMUS MICROFOCUS
Spacegroup: P1
Unit cell:
a: 35.766Å b: 41.526Å c: 46.487Å
α: 89.992° β: 67.921° γ: 76.062°
R-values:
R R work R free
0.178 0.174 0.218
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Targeting ErbB3 Receptor in Cancer with Inhibitory Antibodies from Llama.
Eliseev et al. (2021)
2 more

2 mentions without citation

Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor.
Eliseev et al. (2018)
1 more