› 6fg4

X-ray diffraction
1.1Å resolution

Crystal Structure of the Amyloid-like IIKVIK Segment from the S. aureus Biofilm-associated PSMalpha1

Released:
DOI: 10.2210/pdb6fg4/pdb
PDB entry 6fg4 coloured by chain, front view.
PDB entry 6fg4 coloured by chain, side view.
PDB entry 6fg4 coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Extreme amyloid polymorphism in Staphylococcus aureus virulent PSMα peptides.
Salinas N, Colletier JP, Moshe A, Landau M
Nat Commun 9 3512 (2018)
PMID: 30158633

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo octadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124913 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Psm alpha-1 Chain: A
Molecule details ›
Chain: A
Length: 6 amino acids
Theoretical weight: 715 Da
Source organism: Staphylococcus aureus
Expression system: Not provided
UniProt:
  • Canonical: H9BRQ5 (Residues: 7-12; Coverage: 29%)
Gene names: BN1321_100016, CV021_06525, E1948_02190, E1948_06050, FAF17_11875, G6W63_11185, G6Y24_07035, GO793_01520, GO814_02295, GO941_03880, GO942_04110, GQX37_00175, GZ156_10560, GZ163_06145, H2639_09890, psm alpha-1, psmA

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: C2
Unit cell:
a: 45.27Å b: 4.8Å c: 22.9Å
α: 90° β: 107.65° γ: 90°
R-values:
R R work R free
0.163 0.159 0.194
Expression system: Not provided

Quick links

Citations

14 review citations

Microbial functional amyloids serve diverse purposes for structure, adhesion and defence.
Shanmugam et al. (2019)
13 more

3 mentions without citation

Extreme amyloid polymorphism in Staphylococcus aureus virulent PSMα peptides.
Salinas et al. (2018)
2 more