› 6fyu

X-ray diffraction
2.64Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-207239 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Hemagglutinin Chains: A, D, G
Molecule details ›
Chains: A, D, G
Length: 321 amino acids
Theoretical weight: 34.99 KDa
Source organism: Influenza A virus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A0A097PHH8 (Residues: 19-339; Coverage: 57%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin Chains: B, E, H
Molecule details ›
Chains: B, E, H
Length: 183 amino acids
Theoretical weight: 21.08 KDa
Source organism: Influenza A virus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A0A097PHH8 (Residues: 340-515; Coverage: 31%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B
Single domain antibody SD36 Chains: C, F, I

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
2 bound ligands:
Ligand NAG 9 x NAG
Ligand NA 4 x NA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P212121
Unit cell:
a: 101.424Å b: 128.159Å c: 192.104Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.186 0.216
Expression systems:
  • Trichoplusia ni
  • Homo sapiens

Quick links

Citations

38 review citations

Antibody Structure and Function: The Basis for Engineering Therapeutics.
Chiu et al. (2019)
37 more

5 mentions without citation

Analysis of the conserved protective epitopes of hemagglutinin on influenza A viruses.
Jiao et al. (2023)
4 more