› 6grs

X-ray diffraction
3.4Å resolution

Paired immunoglobulin-like receptor B (PirB) or Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3) full extracellular domain

Released:
DOI: 10.2210/pdb6grs/pdb
PDB entry 6grs coloured by chain, front view.
PDB entry 6grs coloured by chain, side view.
PDB entry 6grs coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure and flexibility of the extracellular region of the PirB receptor.
Vlieg HC, Huizinga EG, Janssen BJC
J Biol Chem 294 4634-4643 (2019)
PMID: 30674550

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185091 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Ig-like domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 606 amino acids
Theoretical weight: 67.46 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8K4V6 (Residues: 25-619; Coverage: 88%)
Gene names: Lilrb3, Pirb
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 54.69Å b: 185.289Å c: 99.08Å
α: 90° β: 105.56° γ: 90°
R-values:
R R work R free
0.258 0.256 0.308
Expression system: Homo sapiens

Quick links

Citations

2 review citations

Leukocyte immunoglobulin-like receptor subfamily B: therapeutic targets in cancer.
Deng et al. (2021)
1 more

2 mentions without citation

A structural discovery journey of streptococcal phages adhesion devices by AlphaFold2.
Goulet et al. (2022)
1 more