› 6h9g

Electron Microscopy
11Å resolution

Influenza A nucleoprotein docked into 3D helical structure of the wild type ribonucleoprotein complex obtained using cryoEM. Conformation 1.

Released:
DOI: 10.2210/pdb6h9g/pdb
PDB entry 6h9g coloured by chain, front view.
PDB entry 6h9g coloured by chain, side view.
PDB entry 6h9g coloured by chain, top view.
Source organism: Influenza A virus (A/Wilson-Smith/1933(H1N1))
Primary publication:
Structural insights into influenza A virus ribonucleoproteins reveal a processive helical track as transcription mechanism.
Coloma R, Arranz R, de la Rosa-Trevín JM, Sorzano COS, Munier S, Carlero D, Naffakh N, Ortín J, Martín-Benito J
Nat Microbiol 5 727-734 (2020)
PMID: 32152587
Related structures: EMD-0175

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147422 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nucleoprotein Chains: A, C
Molecule details ›
Chains: A, C
Length: 469 amino acids
Theoretical weight: 53.11 KDa
Source organism: Influenza A virus (A/Wilson-Smith/1933(H1N1))
UniProt:
  • Canonical: P15682 (Residues: 21-489; Coverage: 94%)
Gene name: NP
Sequence domains: Influenza virus nucleoprotein
Nucleoprotein Chains: B, D
Molecule details ›
Chains: B, D
Length: 19 amino acids
Theoretical weight: 2.11 KDa
Source organism: Influenza A virus (A/Wilson-Smith/1933(H1N1))
UniProt:
  • Canonical: P15682 (Residues: 402-420; Coverage: 4%)
Gene name: NP

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 11Å
Relevant EMDB volumes: EMD-0175

Quick links

Citations

9 review citations

Structure and Function of Influenza Polymerase.
Wandzik et al. (2021)
8 more