› 6hkw

X-ray diffraction
3.09Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172288 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein phosphatase 1 regulatory subunit 7 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 363 amino acids
Theoretical weight: 41.95 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q15435 (Residues: 1-360; Coverage: 100%)
Gene names: PPP1R7, SDS22
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 20 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 177.764Å b: 81.153Å c: 191.958Å
α: 90° β: 104.37° γ: 90°
R-values:
R R work R free
0.211 0.21 0.239
Expression system: Homo sapiens

Quick links

Citations

7 citation in other articles

SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Choy et al. (2019)
6 more

1 mention without citation

Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1.
Heroes et al. (2019)