6hoi

X-ray diffraction
1.14Å resolution

Structure of Beclin1 LIR motif bound to GABARAPL1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-172008 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Gamma-aminobutyric acid receptor-associated protein-like 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 123 amino acids
Theoretical weight: 14.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H0R8 (Residues: 1-117; Coverage: 100%)
Gene names: GABARAPL1, GEC1
Sequence domains: Autophagy protein Atg8 ubiquitin like
Beclin-1 Chains: F, G
Molecule details ›
Chains: F, G
Length: 10 amino acids
Theoretical weight: 1.04 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q14457 (Residues: 93-102; Coverage: 2%)
Gene names: BECN1, GT197

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P212121
Unit cell:
a: 31.99Å b: 54Å c: 138.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.146 0.145 0.166
Expression systems:
  • Escherichia coli
  • Not provided