› 6hxv

X-ray diffraction
1.97Å resolution

Crystal structure of the head and coiled-coil domains of zebrafish CCDC61 (F129E/D130A)

Released:
DOI: 10.2210/pdb6hxv/pdb
PDB entry 6hxv coloured by chain, front view.
PDB entry 6hxv coloured by chain, side view.
PDB entry 6hxv coloured by chain, top view.
Source organism: Danio rerio
Primary publication:
CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Ochi T, Quarantotti V, Lin H, Jullien J, Rosa E Silva I, Boselli F, Barnabas DD, Johnson CM, McLaughlin SH, Freund SMV, Blackford AN, Kimata Y, Goldstein RE, Jackson SP, Blundell TL, Dutcher SK, Gergely F, van Breugel M
Structure 28 674-689.e11 (2020)
PMID: 32375023

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170725 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Centrosomal protein CCDC61 Chains: A, B
Molecule details ›
Chains: A, B
Length: 171 amino acids
Theoretical weight: 19.3 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q08CF3 (Residues: 1-168; Coverage: 33%)
Gene names: ccdc61, zgc:153153

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P212121
Unit cell:
a: 55.36Å b: 76.31Å c: 83.24Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.173 0.238
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 citation in other articles

Structural validation and assessment of AlphaFold2 predictions for centrosomal and centriolar proteins and their complexes.
van Breugel et al. (2022)
3 more

1 mention without citation

CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Ochi et al. (2020)