› 6igw

X-ray diffraction
1.98Å resolution

MPZL1 mutant - S86G, V145G, Q146K,P147T,G148S

Released:
DOI: 10.2210/pdb6igw/pdb
PDB entry 6igw coloured by chain, front view.
PDB entry 6igw coloured by chain, side view.
PDB entry 6igw coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1.
Yu T, Liang L, Zhao X, Yin Y
Biochem Biophys Res Commun 506 883-890 (2018)
PMID: 30392906

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131888 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myelin protein zero-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 15.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O95297 (Residues: 36-162; Coverage: 54%)
Gene names: MPZL1, PZR, UNQ849/PRO1787
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P41212
Unit cell:
a: 39.991Å b: 39.991Å c: 193.37Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.241 0.241 0.247
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 citation in other articles

How Does Protein Zero Assemble Compact Myelin?
Raasakka et al. (2020)
1 more

1 mention without citation

Construction of noninvasive prognostic model of bladder cancer patients based on urine proteomics and screening of natural compounds.
Wan et al. (2023)