› 6iir

X-ray diffraction
2.2Å resolution

Complex structure of the HRP3 PWWP domain with a 10-bp GC-rich DNA

Released:
DOI: 10.2210/pdb6iir/pdb
PDB entry 6iir coloured by chain, front view.
PDB entry 6iir coloured by chain, side view.
PDB entry 6iir coloured by chain, top view.
Source organisms:
Primary publication:
Complex structure of the HRP3 PWWP domain with a 10-bp GC-rich DNA
Wang Z, Tian W
Nucleic Acids Res. (2019)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-120013 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Hepatoma-derived growth factor-related protein 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 100 amino acids
Theoretical weight: 11.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y3E1 (Residues: 1-99; Coverage: 49%)
Gene names: CGI-142, HDGF2, HDGFL3, HDGFRP3
Sequence domains: PWWP domain
10-bp GC-rich DNA Chains: C, D
Molecule details ›
Chains: C, D
Length: 10 nucleotides
Theoretical weight: 3.05 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P31
Unit cell:
a: 33.554Å b: 33.554Å c: 197.913Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.202 0.258
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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