› 6ilp

Electron Microscopy
2.9Å resolution

Cryo-EM structure of full Echovirus 6 particle at PH 7.4

Released:
DOI: 10.2210/pdb6ilp/pdb
PDB entry 6ilp coloured by chain, front view.
PDB entry 6ilp coloured by chain, side view.
PDB entry 6ilp coloured by chain, top view.
Source organism: Echovirus E6
Primary publication:
Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Zhao X, Zhang G, Liu S, Chen X, Peng R, Dai L, Qu X, Li S, Song H, Gao Z, Yuan P, Liu Z, Li C, Shang Z, Li Y, Zhang M, Qi J, Wang H, Du N, Wu Y, Bi Y, Gao S, Shi Y, Yan J, Zhang Y, Xie Z, Wei W, Gao GF
Cell 177 1553-1565.e16 (2019)
PMID: 31104841
Related structures: EMD-9690

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 240-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-166899 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Capsid protein VP1 Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.36 KDa
Source organism: Echovirus E6
Capsid protein VP2 Chain: B
Molecule details ›
Chain: B
Length: 252 amino acids
Theoretical weight: 28.06 KDa
Source organism: Echovirus E6
Capsid protein VP3 Chain: C
Molecule details ›
Chain: C
Length: 238 amino acids
Theoretical weight: 26.38 KDa
Source organism: Echovirus E6
Structure domains: Jelly Rolls
Capsid protein VP4 Chain: D
Molecule details ›
Chain: D
Length: 68 amino acids
Theoretical weight: 7.33 KDa
Source organism: Echovirus E6

Ligands and Environments

1 bound ligand:
Ligand SPH 1 x SPH
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.9Å
Relevant EMDB volumes: EMD-9690

Quick links

Citations

10 review citations

The Neonatal Fc Receptor (FcRn): A Misnomer?
Pyzik et al. (2019)
9 more

4 mentions without citation

Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Zhao et al. (2019)
3 more