› 6im5

X-ray diffraction
1.7Å resolution

YAP-binding domain of human TEAD1

Released:
DOI: 10.2210/pdb6im5/pdb
PDB entry 6im5 coloured by chain, front view.
PDB entry 6im5 coloured by chain, side view.
PDB entry 6im5 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal Structure of the YAP-binding Domain of Human TEAD1
Mo Y, Lee HS, Lee CH, Lim HJ, Park SJ, Shin H-C, Kim C-H, Kim SJ, Ku B
Bull.Korean Chem.Soc. 40 74-77 (2019)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151213 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional enhancer factor TEF-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 233 amino acids
Theoretical weight: 26.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P28347 (Residues: 210-426; Coverage: 51%)
Gene names: TCF13, TEAD1, TEF1
Sequence domains: YAP binding domain
Structure domains: Coagulation Factor XIII; Chain A, domain 1

Ligands and Environments

1 bound ligand:
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P212121
Unit cell:
a: 36.537Å b: 89.356Å c: 135.569Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.195 0.23
Expression system: Escherichia coli

Quick links