› 6iom

X-ray diffraction
2.59Å resolution

Crystal structure of human C4.4A

Released:
DOI: 10.2210/pdb6iom/pdb
PDB entry 6iom coloured by chain, front view.
PDB entry 6iom coloured by chain, side view.
PDB entry 6iom coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal Structures of Human C4.4A Reveal the Unique Association of Ly6/uPAR/alpha-neurotoxin Domain
Jiang YB, Lin L, Chen S, Jiang LG, Kriegbaum MC, Gardsvoll H, Hansen LV, Li J, Ploug M, Yuan C, Huang MD
Int J Biol Sci 16 981-993 (2020)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131882 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Ly6/PLAUR domain-containing protein 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 201 amino acids
Theoretical weight: 21.14 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: O95274 (Residues: 31-231; Coverage: 64%)
Gene names: C4.4A, LYPD3, UNQ491/PRO1007
Sequence domains: u-PAR/Ly-6 domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 5 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2221
Unit cell:
a: 57.055Å b: 120.156Å c: 169.431Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.198 0.256
Expression system: Drosophila melanogaster

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