› 6ith

Solution NMR

Structure of the transmembrane domain of syndecan 2 in micelles

Released:
DOI: 10.2210/pdb6ith/pdb
PDB entry 6ith coloured by chain, ensemble of 15 models, front view.
PDB entry 6ith coloured by chain, ensemble of 15 models, side view.
PDB entry 6ith coloured by chain, ensemble of 15 models, top view.
Source organism: Homo sapiens
Primary publication:
Secondary structure and topology of the transmembrane domain of Syndecan-2 in detergent micelles.
Li Q, Ng HQ, Kang C
FEBS Lett 593 554-561 (2019)
PMID: 30742705

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152719 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Syndecan-2 Chain: A
Molecule details ›
Chain: A
Length: 41 amino acids
Theoretical weight: 4.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P34741 (Residues: 143-173; Coverage: 17%)
Gene names: HSPG1, SDC2
Sequence domains: Syndecan domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 41%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Structures and Dynamics of Dengue Virus Nonstructural Membrane Proteins.
Li et al. (2022)
2 other articles

3 mentions without citation

An in silico scientific basis for LL-37 as a therapeutic for Covid-19.
Lokhande et al. (2022)
2 more