› 6ixg

X-ray diffraction
3.8Å resolution

Crystal structure of native apo SH3BP5 (P41)

Released:
DOI: 10.2210/pdb6ixg/pdb
PDB entry 6ixg coloured by chain, front view.
PDB entry 6ixg coloured by chain, side view.
PDB entry 6ixg coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of guanine nucleotide exchange for Rab11 by SH3BP5.
Goto-Ito S, Morooka N, Yamagata A, Sato Y, Sato K, Fukai S
Life Sci Alliance 2 (2019)
PMID: 30872413

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129918 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SH3 domain-binding protein 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 228 amino acids
Theoretical weight: 26.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60239 (Residues: 41-266; Coverage: 50%)
Gene names: SAB, SH3BP5
Sequence domains: SH3 domain-binding protein 5 (SH3BP5)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P41
Unit cell:
a: 79.958Å b: 79.958Å c: 94.353Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.242 0.278
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Structural Insights into the Regulation Mechanism of Small GTPases by GEFs.
Toma-Fukai et al. (2019)
2 more

1 mention without citation

Structural basis of guanine nucleotide exchange for Rab11 by SH3BP5.
Goto-Ito et al. (2019)