› 6j18

X-ray diffraction
2Å resolution

ATPase

Released:
DOI: 10.2210/pdb6j18/pdb
PDB entry 6j18 coloured by chain, front view.
PDB entry 6j18 coloured by chain, side view.
PDB entry 6j18 coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Primary publication:
Structural insights into substrate recognition by the type VII secretion system.
Wang S, Zhou K, Yang X, Zhang B, Zhao Y, Xiao Y, Yang X, Yang H, Guddat LW, Li J, Rao Z
Protein Cell 11 124-137 (2020)
PMID: 31758528

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161842 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ESX-5 secretion system protein EccC5 Chain: A
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 34.37 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WNA5 (Residues: 1116-1391; Coverage: 20%)
Gene names: Rv1783, eccC5

Ligands and Environments

2 bound ligands:
Ligand ATP 1 x ATP
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P65
Unit cell:
a: 89.161Å b: 89.161Å c: 62.637Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.167 0.2
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Type VII secretion systems: structure, functions and transport models.
Rivera-Calzada et al. (2021)
1 more

1 mention without citation

Structural insights into substrate recognition by the type VII secretion system.
Wang et al. (2020)