› 6jbu

X-ray diffraction
1.85Å resolution

High resolution crystal structure of human FLRT3 LRR domain in complex with mouse CIRL3 Olfactomedin like domain

Released:
DOI: 10.2210/pdb6jbu/pdb
PDB entry 6jbu coloured by chain, front view.
PDB entry 6jbu coloured by chain, side view.
PDB entry 6jbu coloured by chain, top view.
Source organisms:
Entry authors: Liu H, Li Z, Xu F

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182366 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Adhesion G protein-coupled receptor L3 Chain: A
Molecule details ›
Chain: A
Length: 276 amino acids
Theoretical weight: 31.65 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q80TS3 (Residues: 203-461; Coverage: 17%)
Gene names: Adgrl3, Kiaa0768, Lec3, Lphn3
Sequence domains: Olfactomedin-like domain
Leucine-rich repeat transmembrane protein FLRT3 Chain: B
Molecule details ›
Chain: B
Length: 347 amino acids
Theoretical weight: 39.61 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9NZU0 (Residues: 29-358; Coverage: 53%)
Gene names: FLRT3, KIAA1469, UNQ856/PRO1865
Sequence domains: Leucine rich repeat

Ligands and Environments

4 bound ligands:
Ligand PO4 2 x PO4
Ligand NA 3 x NA
Ligand EDO 4 x EDO
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P3121
Unit cell:
a: 121.135Å b: 121.135Å c: 83.413Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.208 0.234
Expression system: Homo sapiens

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