6jfv

X-ray diffraction
2.6Å resolution

The crystal structure of 2B-2B complex from keratins 5 and 14 (C367A mutant of K14)

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-135886 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Keratin, type I cytoskeletal 14 Chains: A, C
Molecule details ›
Chains: A, C
Length: 95 amino acids
Theoretical weight: 11.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02533 (Residues: 327-421; Coverage: 20%)
Gene name: KRT14
Sequence domains: Intermediate filament protein
Keratin, type II cytoskeletal 5 Chains: B, D
Molecule details ›
Chains: B, D
Length: 98 amino acids
Theoretical weight: 11.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13647 (Residues: 379-476; Coverage: 17%)
Gene name: KRT5
Sequence domains: Intermediate filament protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P41
Unit cell:
a: 56.149Å b: 56.149Å c: 222.054Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.201 0.246
Expression system: Escherichia coli