6jkj

X-ray diffraction
1.9Å resolution

Crystal structure of human SPSB2 in the apo-state

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of the SPRY domain of human SPSB2 in the apo state.
Acta Crystallogr F Struct Biol Commun 75 412-418 (2019)
PMID: 31204687

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-189234 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SPRY domain-containing SOCS box protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 209 amino acids
Theoretical weight: 22.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99619 (Residues: 22-220; Coverage: 76%)
Gene names: GRCC9, SPSB2, SSB2
Sequence domains: SPRY domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 32.45Å b: 75.1Å c: 79.2Å
α: 90° β: 101.38° γ: 90°
R-values:
R R work R free
0.219 0.217 0.27
Expression system: Escherichia coli