6jm4

X-ray diffraction
3.2Å resolution

The crystal structure of PB1 homo-dimer of human P62/SQSTM1

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171722 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Sequestosome-1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 102 amino acids
Theoretical weight: 11.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13501 (Residues: 1-102; Coverage: 23%)
Gene names: ORCA, OSIL, SQSTM1
Sequence domains: PB1 domain
Sequestosome-1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 102 amino acids
Theoretical weight: 11.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13501 (Residues: 1-102; Coverage: 23%)
Gene names: ORCA, OSIL, SQSTM1
Sequence domains: PB1 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 11C
Spacegroup: C2
Unit cell:
a: 112.483Å b: 53.517Å c: 61.457Å
α: 90° β: 94.287° γ: 90°
R-values:
R R work R free
0.243 0.239 0.276
Expression system: Escherichia coli BL21(DE3)