Function and Biology Details
Reaction catalysed:
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-107388 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
p130
Molecule details ›
Chains: A, C, E
Length: 406 amino acids
Theoretical weight: 45.88 KDa
Source organism: Chikungunya virus
Expression system: Trichoplusia ni
UniProt:
Structure domains:
Length: 406 amino acids
Theoretical weight: 45.88 KDa
Source organism: Chikungunya virus
Expression system: Trichoplusia ni
UniProt:
- Canonical:
C8YZ73 (Residues: 262-666; Coverage: 33%)
Structure domains:
Alphavirus E1 glycoprotein domain-containing protein
Molecule details ›
Chains: B, D, F
Length: 432 amino acids
Theoretical weight: 46.03 KDa
Source organism: Chikungunya virus
Expression system: Trichoplusia ni
UniProt:
Length: 432 amino acids
Theoretical weight: 46.03 KDa
Source organism: Chikungunya virus
Expression system: Trichoplusia ni
UniProt:
- Canonical: A4L787 (Residues: 101-512; Coverage: 76%)
Matrix remodeling-associated protein 8
Molecule details ›
Chains: M, N, O
Length: 269 amino acids
Theoretical weight: 30.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Immunoglobulin V-set domain
Length: 269 amino acids
Theoretical weight: 30.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9BRK3 (Residues: 25-292; Coverage: 63%)
Sequence domains: Immunoglobulin V-set domain
