Function and Biology Details
Reaction catalysed:
K(+)(out) + ATP + H2O + H(+)(in) = K(+)(in) + ADP + phosphate +2 H(+)(out).
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Sodium/potassium-transporting ATPase subunit beta
- P-type ATPase, cytoplasmic domain N
- P-type ATPase
- Cation-transporting P-type ATPase, N-terminal
- P-type ATPase subfamily IIC, subunit alpha
- Sodium/potassium-transporting ATPase subunit beta superfamily
- Cation-transporting P-type ATPase, C-terminal
- P-type ATPase, phosphorylation site
6 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Hydrogen:potassium-exchanging ATPase complex (preferred)
PDBe Complex ID:
PDB-CPX-148371 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Potassium-transporting ATPase alpha chain 1
Molecule details ›
Chain: A
Length: 987 amino acids
Theoretical weight: 109.22 KDa
Source organism: Sus scrofa
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 987 amino acids
Theoretical weight: 109.22 KDa
Source organism: Sus scrofa
Expression system: Homo sapiens
UniProt:
- Canonical:
P19156 (Residues: 49-1034; Coverage: 95%)
Sequence domains:
Potassium-transporting ATPase subunit beta
Molecule details ›
Chain: B
Length: 289 amino acids
Theoretical weight: 32.98 KDa
Source organism: Sus scrofa
Expression system: Homo sapiens
UniProt:
Sequence domains: Sodium / potassium ATPase beta chain
Length: 289 amino acids
Theoretical weight: 32.98 KDa
Source organism: Sus scrofa
Expression system: Homo sapiens
UniProt:
- Canonical: P18434 (Residues: 2-286; Coverage: 98%)
Sequence domains: Sodium / potassium ATPase beta chain
