Function and Biology Details
Reaction catalysed:
ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
ATP8A1-CDC50A P4-ATPase complex (preferred)
PDBe Complex ID:
PDB-CPX-192631 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Phospholipid-transporting ATPase IA
Molecule details ›
Chain: A
Length: 1154 amino acids
Theoretical weight: 130.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 1154 amino acids
Theoretical weight: 130.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9Y2Q0 (Residues: 1-1164; Coverage: 99%)
Sequence domains:
Cell cycle control protein 50A
Molecule details ›
Chain: C
Length: 361 amino acids
Theoretical weight: 40.73 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: LEM3 (ligand-effect modulator 3) family / CDC50 family
Length: 361 amino acids
Theoretical weight: 40.73 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q9NV96 (Residues: 1-361; Coverage: 100%)
Sequence domains: LEM3 (ligand-effect modulator 3) family / CDC50 family
