› 6kfg

Electron Microscopy
3.8Å resolution

Undocked INX-6 hemichannel in detergent

Released:
DOI: 10.2210/pdb6kfg/pdb
PDB entry 6kfg coloured by chain, front view.
PDB entry 6kfg coloured by chain, side view.
PDB entry 6kfg coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids.
Burendei B, Shinozaki R, Watanabe M, Terada T, Tani K, Fujiyoshi Y, Oshima A
Sci Adv 6 eaax3157 (2020)
PMID: 32095518
Related structures: EMD-9972

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193603 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Innexin-6 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 389 amino acids
Theoretical weight: 45.17 KDa
Source organism: Caenorhabditis elegans
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9U3N4 (Residues: 1-389; Coverage: 100%)
Gene names: C36H8.2, inx-6, opu-6
Sequence domains: Innexin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-9972
Expression system: Spodoptera frugiperda

Quick links

Citations

1 review citation

Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions.
Bernardi et al. (2023)
14 other articles

2 mentions without citation

On the molecular nature of large-pore channels.
Syrjanen et al. (2021)
1 more