Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Ubiquitin carboxyl-terminal hydrolase 19 (preferred)
PDBe Complex ID:
PDB-CPX-131803 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin carboxyl-terminal hydrolase 19
O94966Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
63%
Refinement method:
molecular dynamics
Expression system: Escherichia coli
