› 6khx

X-ray diffraction
2.58Å resolution

Crystal structure of Prx from Akkermansia muciniphila

Released:
DOI: 10.2210/pdb6khx/pdb
Model geometry
Fit model/data
PDB entry 6khx coloured by chain, front view.
PDB entry 6khx coloured by chain, side view.
PDB entry 6khx coloured by chain, top view.
Source organism: Akkermansia muciniphila
Primary publication:
Crystal structure of Akkermansia muciniphila peroxiredoxin reveals a novel regulatory mechanism of typical 2-Cys Prxs by a distinct loop.
Li M, Wang J, Xu W, Wang Y, Zhang M, Wang M
FEBS Lett 594 1550-1563 (2020)
PMID: 32027024

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo decamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-242635 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxiredoxin Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 215 amino acids
Theoretical weight: 23.92 KDa
Source organism: Akkermansia muciniphila
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

1 bound ligand:
Ligand CA 8 x CA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21212
Unit cell:
a: 132.733Å b: 211.371Å c: 92.802Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.218
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 mention without citation

Peroxiredoxins wear many hats: Factors that fashion their peroxide sensing personalities.
Bolduc et al. (2021)