› 6kxw

X-ray diffraction
3.7Å resolution

Crystal structure of human aquaporin AQP7 in bound to glycerol

Released:
DOI: 10.2210/pdb6kxw/pdb
PDB entry 6kxw coloured by chain, front view.
PDB entry 6kxw coloured by chain, side view.
PDB entry 6kxw coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The structural basis for glycerol permeation by human AQP7
Zhang L, Yao D, Xia Y, Zhang Q, Zhou F, Wang Q, Qin A, Zhao J, Li D, Li Y, Zhou L, Cao Y
Sci Bull (Beijing) 66 1550-1558 (2020)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126992 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aquaporin-7 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 342 amino acids
Theoretical weight: 37.26 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O14520 (Residues: 1-342; Coverage: 100%)
Gene names: AQP7, AQP7L, AQP9
Sequence domains: Major intrinsic protein

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P212121
Unit cell:
a: 93.508Å b: 106.286Å c: 214.416Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.271 0.268 0.322
Expression system: Spodoptera frugiperda

Quick links