› 6kzg

X-ray diffraction
2Å resolution

14-3-3 protein in Complex with CIC S301 phosphorylated peptide

Released:
DOI: 10.2210/pdb6kzg/pdb
PDB entry 6kzg coloured by chain, front view.
PDB entry 6kzg coloured by chain, side view.
PDB entry 6kzg coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wen Y, Shao Y

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150977 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein theta Chains: A, B
Molecule details ›
Chains: A, B
Length: 263 amino acids
Theoretical weight: 29.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P27348 (Residues: 2-234; Coverage: 95%)
Gene name: YWHAQ
Sequence domains: 14-3-3 protein
Protein capicua homolog Chains: C, Q
Molecule details ›
Chains: C, Q
Length: 8 amino acids
Theoretical weight: 949 Da
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q96RK0 (Residues: 298-305; Coverage: 1%)
Gene names: CIC, KIAA0306

Ligands and Environments

No bound ligands
1 modified residue:
Ligand SEP 2 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P212121
Unit cell:
a: 69.657Å b: 79.487Å c: 106.261Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.191 0.231
Expression system: Escherichia coli BL21

Quick links