› 6l4g

X-ray diffraction
3.3Å resolution

Crystal structure of human NDRG3 I171M/S176H mutant

Released:
DOI: 10.2210/pdb6l4g/pdb
PDB entry 6l4g coloured by chain, front view.
PDB entry 6l4g coloured by chain, side view.
PDB entry 6l4g coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein.
Kim KR, Kim KA, Park JS, Jang JY, Choi Y, Lee HH, Lee DC, Park KC, Yeom YI, Kim HJ, Han BW
Biomolecules 10 (2020)
PMID: 31935861

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193723 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein NDRG3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 375 amino acids
Theoretical weight: 41.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UGV2 (Residues: 1-375; Coverage: 100%)
Gene name: NDRG3
Sequence domains: Ndr family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
R-values:
R R work R free
0.198 0.196 0.226
Expression system: Escherichia coli

Quick links

Citations

4 citation in other articles

Differential expression and hypoxia-mediated regulation of the N-myc downstream regulated gene family.
Le et al. (2021)
3 more

1 mention without citation

Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein.
Kim et al. (2020)