› 6lar

Electron Microscopy
3.7Å resolution

Structure of ESX-3 complex

Released:
DOI: 10.2210/pdb6lar/pdb
PDB entry 6lar coloured by chain, front view.
PDB entry 6lar coloured by chain, side view.
PDB entry 6lar coloured by chain, top view.
Source organism: Mycolicibacterium smegmatis MC2 155
Entry authors: Wang SH, Zhou KX, Li J, Rao ZH
Related structures: EMD-0862

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
PDBe Complex ID:
PDB-CPX-106244 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
ESX-3 secretion system ATPase EccB3 Chains: A, I
Molecule details ›
Chains: A, I
Length: 518 amino acids
Theoretical weight: 53.68 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli
UniProt:
  • Canonical: A0QQ39 (Residues: 1-518; Coverage: 100%)
Gene names: MSMEG_0616, MSMEI_0600, eccB3
Sequence domains: Type VII secretion system ESX-1, transport TM domain B
ESX-3 secretion system protein EccD3 Chains: B, C, E, H
Molecule details ›
Chains: B, C, E, H
Length: 475 amino acids
Theoretical weight: 48.29 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli
UniProt:
  • Canonical: A0QQ46 (Residues: 1-475; Coverage: 100%)
Gene names: MSMEG_0623, MSMEI_0607, eccD3, snm
Sequence domains: WXG100 protein secretion system (Wss), protein YukD
ESX-3 secretion system protein EccC3 Chains: F, J
Molecule details ›
Chains: F, J
Length: 449 amino acids
Theoretical weight: 49.9 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli
UniProt:
  • Canonical: A0QQ40 (Residues: 1-431; Coverage: 33%)
Gene names: MSMEG_0617, MSMEI_0601, eccC3
ESX-3 secretion system protein EccE3 Chains: D, G
Molecule details ›
Chains: D, G
Length: 309 amino acids
Theoretical weight: 33.23 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli
UniProt:
  • Canonical: A0QQ48 (Residues: 1-309; Coverage: 100%)
Gene names: MSMEG_0626, MSMEI_0609, eccE3
Sequence domains: Putative type VII ESX secretion system translocon, EccE

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-0862
Expression system: Escherichia coli

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