› 6lcs

X-ray diffraction
2.6Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214103 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
VH-SARAH Chain: A
Molecule details ›
Chain: A
Length: 171 amino acids
Theoretical weight: 19.95 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
VL-SARAH Chain: B
Molecule details ›
Chain: B
Length: 161 amino acids
Theoretical weight: 18.04 KDa
Source organism: Mus musculus
Expression system: Escherichia coli

Ligands and Environments

2 bound ligands:
Ligand E9R 1 x E9R
Ligand PO4 3 x PO4
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: P41212
Unit cell:
a: 91.15Å b: 91.15Å c: 119.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.214 0.26
Expression system: Escherichia coli

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Citations

1 citations in other articles

Molecular Dynamics-Based Design and Biophysical Evaluation of Thermostable Single-Chain Fv Antibody Mutants Derived from Pharmaceutical Antibodies.
Okazaki et al. (2023)