› 6ljf

X-ray diffraction
1.5Å resolution

Crystal structure of gelsolin G3 domain (calcium condition)

Released:
DOI: 10.2210/pdb6ljf/pdb
Model geometry
Fit model/data
PDB entry 6ljf coloured by chain, front view.
PDB entry 6ljf coloured by chain, side view.
PDB entry 6ljf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Novel inter-domain Ca2+-binding site in the gelsolin superfamily protein fragmin.
Takeda S, Fujiwara I, Sugimoto Y, Oda T, Narita A, Maéda Y
J Muscle Res Cell Motil 41 153-162 (2020)
PMID: 31863323

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139010 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gelsolin Chains: A, B
Molecule details ›
Chains: A, B
Length: 101 amino acids
Theoretical weight: 11.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P06396 (Residues: 297-397; Coverage: 13%)
Gene name: GSN
Sequence domains: Gelsolin repeat

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: AichiSR BEAMLINE BL2S1
Spacegroup: C2
Unit cell:
a: 58.39Å b: 41.81Å c: 84.59Å
α: 90° β: 105.232° γ: 90°
R-values:
R R work R free
0.174 0.174 0.184
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Susceptibility of cytoskeletal-associated proteins for tumor progression.
Ayanlaja et al. (2021)
1 more